We are aware that the majority of germs pose a risk to both people and animals. There are other microorganisms in the Ganga River. Examining the kind and quantity of bacteria found in contaminated and uncontaminated environments is fascinating. The large quantity of these bacteria causes numerous ailments in people and animals, even in the face of substantial untreated and contaminated effluent drainage from the leather industry, pesticide industry, paper mills, metropolitan centers, and other sources. The many types of bacteria found in the Ganga River and their interactions with their animal hosts were discovered in a contaminated aquatic environment. For the study of the Ganga Raebareli UP, a total of three sampling sites were chosen. Samples were taken from Gengaso Ghat, Dalmau Ghat, Gokana, or Gokarna Ghat Raebareli.