Mechanisms of Heavy Metal Tolerance in Plants: A Molecular Perspective

Heavy metal contamination poses a significant threat to plant growth and productivity, impacting agricultural systems and food safety. Understanding the molecular mechanisms underlying heavy metal tolerance in plants is crucial for developing strategies to mitigate these effects. This review explores the latest advances in the molecular basis of heavy metal tolerance, including metal uptake, transport, sequestration, and detoxification. We discuss the roles of key genes, proteins, and signaling pathways involved in these processes, with a focus on phytochelatins, metallothioneins, and transporter proteins. Additionally, we highlight the genetic and biotechnological approaches used to enhance heavy metal tolerance in plants. Future research directions and potential applications for phytoremediation and sustainable agriculture are also addressed.