Diabetic foot ulcers (DFUs) pose a significant challenge in healthcare, often leading to severe complications and prolonged healing times. The development of advanced wound dressings tailored to the unique needs of DFUs is critical for effective management and improved patient outcomes. In recent years, electrospinning technology has emerged as a promising approach for fabricating nano-fibrous wound dressings with enhanced properties. This review explores the fabrication and characterization of cellulose acetate-EUSOL/polyvinyl alcohol-curcumin (CA-EUSOL/PVA-CUR) electrospun dressings for DFU treatment. We discuss the synthesis process of CA-EUSOL and its combination with polyvinyl alcohol and curcumin, highlighting the synergistic effects in promoting wound healing. Furthermore, we delve into the characterization techniques used to assess the structural, mechanical, and biological properties of these dressings. Additionally, we review preclinical and clinical studies evaluating the efficacy and safety of CA-EUSOL/PVA-CUR electrospun dressings in DFU management. Through a comprehensive analysis, this review aims to provide insights into the development of innovative wound care solutions for DFUs using electrospun dressings.