Several chemicals, including salicylic acid, acibenzolar-S-methyl, acetylsalicylic acid, nicotinic acid, jasmonic acid, and oxalic acid, have been shown to induce resistance in various crops. Marine algae, with their vast array of complex natural products, represent a promising source of novel bioactive compounds that can enhance plant resilience by providing protection against stress induced by pathogens. This study aimed to evaluate the effects of various resistance-inducing chemicals and seaweed extracts on the activation of defense enzymes in Xanthomonas oryzae pv. oryzae (Xoo)-challenged paddy plants. The findings may contribute to the development of eco-friendly strategies for managing bacterial diseases in rice cultivation